Asset profile

obudanersen · Ionis (IONS)

Indication: Angelman syndrome
Also known as: ION582

Company

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare di…

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On the calendar

Aug 2027

~ Aug 2027

IONSIonis

obudanersen: Phase 3 trial NCT06914609 expected to finish collecting primary-endpoint data (topline results usually follow)

Trial primary completionClinicalTrials.govMonth only

May 2028

~ May 2028

IONSIonis

obudanersen: Phase 3 trial NCT07782827 expected to finish collecting primary-endpoint data (topline results usually follow)

Trial primary completionClinicalTrials.govMonth only

Mar 2029

~ Mar 2029

IONSIonis

obudanersen: Phase 1/Phase 2 trial NCT05127226 expected to finish collecting primary-endpoint data (topline results usually follow)

Trial primary completionClinicalTrials.govMonth only

Timeline

Newest first.

Sep 28, 2026

03:22 PM

IONSIonis

obudanersen · NCT07782827 registry update

Trial registry changeClinicalTrials.gov Open record1 update

Jul 6, 2026

11:00 AM

IONSIonis

Ionis completes pivotal-cohort enrollment in Phase 3 REVEAL study of obudanersen

Trial registry changeCompany press release

Registered trials

Registry ID	Phase	Status	Primary completion	Enrollment	Sites
NCT06914609	Phase 3	Active, not recruiting	Aug 1, 2027	156	18 of 41 sites in the United States
NCT07782827	Phase 3	Recruiting	May 1, 2028	30	1 of 1 sites in the United States
NCT05127226	Phase 1/2	Active, not recruiting	Mar 1, 2029	71	6 of 11 sites in the United States

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