Biopharma · FDA Approvals · Stock
Annovis Bio Inc, a clinical stage drug platform company, develops drugs to treat neurodegeneration in the United States. The company's flagship candidate, buntanetap, is in clinical trials for the treatment of Alzheimer's disease, Parkinson's disease, and Lewy body dementia. It also develops ANVS405, which is in phase …
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buntanetap · NCT07284784 registry update
countries: {'total_sites': 27, 'us_sites': 27} → {'total_sites': 29, 'us_sites': 29}
Annovis completes full enrollment of Phase 3 buntanetap AD trial
The pivotal Phase 3 trial of buntanetap in early Alzheimer’s disease has reached full enrollment of 850 patients, exceeding the original target. The dual-readout design remains unchanged, with symptomatic data expected in Q1 2027 and disease-modifying data in Q1 2028, each intended to support a separate NDA submission.
Annovis closes AD Phase 3 screening; 85% enrolled
Annovis closed new screening for its pivotal Phase 3 AD trial (NCT06709014) on 15 May 2026 after reaching a sufficient pool to complete randomization. The study remains on track for full enrollment in summer 2026, with symptomatic data expected ~6 months after last patient dosed and disease-modifying data at 18 months.
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